Trimix Injection

Trimix Injection Divine Overseas

Trimix Injection

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Trimix Injection is Administered as a penile self-injection injected alongside the penis shaft. Trimix is a compound medicine made of Papaverine, Phentolamine & Prostaglandin E1 are, on their own, indicated for a vast number of different conditions. These medicines are used together in Trimix Injection for the treatment of erectile dysfunction and to improve the blood flow to the penis, which gives you a firm & prolonging erection.

What is Trimix Injection?

Trimix is an injectable  medicine used to treat erectile dysfunction by improving blood flow. 3 active ingredients of Trimix are Papaverine, Phentolamine, and Prostaglandin E1, which increase blood flow to the penis and provide a firm erection. It is usually used as an alternative or second-line medication to PDE-5 inhibitors to treat erectile dysfunction. That’s why Trimix Injection is best suited for men who are not able to take PDE-5 medicines as treatment for erectile dysfunction.


Who Needs Trimix Injection?

Trimix Injection is one of the treatment methods for erectile dysfunction. It is only prescribed to men who are not able to get an erection despite using PDE5 inhibitors for the treatment of erectile dysfunction. However, doctors do not prescribe Trimix injection directly as a treatment method for ED. They First go with the medicine and suggest PDE5 inhibitor medicine to the patients and check their results. If the doctor finds out that PDE-5 Inhibitor medicine is not working on patients, then they prefer Trimix for ED treatment.

How Does Trimix Injection Work?

Trimix Injection contains three medicines from complementary classes designed to act synergic ally, mixed into a sterile injection. 




  • A medicine that causes blood vessels to expand (vasodilator).
  • It produces an erection by allowing for increased blood flow to the penis.
  • Experimental data, performed in-vitro, displays papaverine acting to relax the penile arteries, the cavernosal sinusoids, and the penile veins.


  • When injected into the penis, it induces an erection by relaxing and dilating the blood vessels of the penis, as well as by elevating cardiac output.
  • Side effects of phentolamine are rare.

Prostaglandin E1

  • A potent hormone-like substance that induces erection by relaxing the penis’s blood vessels and dilating cavernoma arteries-dilation of the cavernosal arteries.
  • It is accompanied by increased arterial inflow velocity and increased venous outflow resistance allowing for more blood into the penis and less blood out.

How & When to Use Trimix Injections:

  • Ideally, the trimix injections should be administered just prior to foreplay.
  • It is administered via intracavernosal injection and should produce an erection in 5 to 20 minutes and can be expected to last up to one hour. You can even feel erection after ejaculation so don’t worry about it.
  • To prevent bruising, apply firm pressure to the injection site for 5 minutes after injecting.
  • Do not use TriMix Injection more than two times a week; use at least 24 hours apart.
  • There is a possibility of needle breakage with the use of TriMix Injection: you should pay careful attention to your doctor’s instructions and handle the syringe and needle properly.

How to Self-Administer Trimix

As we mentioned, Trimix is an Injectable medicine that can be Self-Administered during use. You can use it 2 -3 times a week but keep an interval of 24 hours. But before injecting it, you should keep these essential things in mind like

  • Wash your hand and genital properly and wipe them well with the alcohol pad
  • Clean the top of the Syringe with an alcohol pad
  • Find an Injectable position in the penis, Don’t inject trimix at the top or bottom of the penis. Find an Injectable place sideways while avoiding arteries or veins. Draw out the prescribed amount of medicine from the container while ensuring no air bubbles present in the Syringe.
  • Clean the injectable position with a fresh alcohol pad of cotton
  • Insert the Syringe Containing Trimix into the penis, slowly press the syringe top, release the trimix into the corpora cavernosa of the penis & Slowly Remove the Syringe.
  • Remove the Syringe from the penis and clean the injected place with an alcohol pad & gently massage the area.

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